LinkedInLesley Harrison

Lesley Harrison

Laboratory Technician at Duesmann & Hensel Recycling UK

Location
Redhill, United Kingdom
Industry
Pharmaceuticals
Previous
  1. GSK,
  2. Novartis,
  3. Novartis,Horsham,West Sussex
Education
  1. North East Surrey College of Technology
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North East Surrey College of Technology

North East Surrey College of Technology

Biochemistry,Physiology& Pharmacology

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Background

Experience

Laboratory Technician

Duesmann & Hensel Recycling UK
– Present (3 years)Slinfold, West Sussex

Company is an extension of D&H Recycling, Germany, a company specialising in the recovery of precious metals from catalytic convertors.Responsible for the running and the organisation of the laboratory,dry sample preparation of processed monolith and determination of precious metal content (platinum,palladium and rhodium) using X-ray fluorescence (XRF) analysis.

Analytical Scientist

GSK
(12 years 1 month)

Main role to provide timely and accurate and efficient evaluations of finished product and stability samples according to appropriate standards to help gain quality assurance of formulated products.
Good knowledge of laboratory analytical techniques/methods.
Analysed a wide range of products including tablets. capsules, ampoule injections and topical medications.
12 years experience of testing products, which involves setting up and running of HPLC, Automated Robotic Systems(TPW, Multidose), TLC ID techniques and UV Spectrometry and Dissolution bath manual methods.
Computer literate in LIMS, Empower Chromatography(CDS), Microsoft Excel, Word and Outlook software.
Supervised, maintained and calibrated laboratory equipment.
Reviewing system log books to ensure compliance for audit readiness.
Strong understanding of GLP/GMP standards.
Performed and reported analysis of laboratory samples following SOPs and validated product testing methods.
Completed Periodic Product reviews.

Analytical Associate

Novartis
(less than a year)

Quality control, Pharmaceutical Operations.
Novartis, Horsham, West Sussex

Technician in Pharmaceutical& Analytical Development Department (temporary position)

Novartis,Horsham,West Sussex
(7 months)

Assisted in the development and validation of dissolution methods to determine dissolution rate constants of various respiratory compounds in artificial lung fluid.

Bio-analyst in Department of Pharmacokinectics & Metabolism Division

Roche Products, Welwyn Garden City,Herts
(1 year 2 months)

Measurement of drug concentrations in biological samples from pharmacokinectic studies, required for the registration of new pharmaceutical products.
Analysed drug inhibition of ACE in plasma and urine samples obtained from hypertensive patients using radio enzymatic assay techniques.
Attended DMDG (Drug Metabolism & Pharmacokinectics) training course at University of Surrey.

Drug Analyst in the Department of Drug Analysis

Smith Kline and French Research Limited, The Frythe, Welwyn,Herts
(1 year 3 months)

Analysed plasma samples obtained from pre-clinical studies using liquid-solid extraction techniques and HPLC with electrochemical detection.
Other duties involved logging on sample codes together with various drug treatments and the operating protocol into LIMS computer software.

Analytical Assistant in The Department of Analytical Chemistry

BIOS Ltd (Consultancy and Contract Research Company)
(1 year 7 months)

Worked on research projects contracted out by pharmaceutical research and development companies.
Determination of drug concentrations in human plasma obtained from human clinical studies, using solid-phase (bond-elute) extraction techniques followed by HPLC analysis with fluorometric detection.
Analysing and reporting of results using computer software.
Assisted with the organisation and completion of human clinical trials.
Co-authorship of a paper which was submitted for publication in the Journal of Chromatography entitled `The determination of Salbutamol in human plasma by HPLC on a Silica column after Solid phase extraction'. The authors were ME Pickup, LP Harrison from BIOS, and RE Bland and RJN Tanner from the Glaxo Group,Ware.

Technical Officer in the Enzymology Laboratory(Department of Biochemistry)

British Industrial Biologiocal Research Association (BIBRA),Carshalton Beeches, Surrey
(2 years 1 month)

Assisted in the research to determine the toxic effects of high fat diets and chemicals such as hypo-lipidimic drugs, pesticides and plastizers in rat livers and primary rat hepatocyte cultures.
Measured xenobiotioc metabolising enzyme activity in rat liver tissue and hepatocyte cultures using UV spectroscopy and fluorometric enzyme assay methods.
Results published in scientific papers and reported to MAFF (Ministry of Agriculture, Fisheries and Food)

Laboratory Technician in Skin Care Research Department

Beecham Products Research Department, Weybridge, Surrey
(4 years 10 months)

Organised and conducted approved studies to determine the physical and biological characteristics of human skin and the effects of applying topical materials.
Measurements were determined using Talysurf Profileometry and Evaporimetry equipment.
Other duties involved presenting studies at 3 monthly review meetings

Skills

  • Validation
  • HPLC
  • LIMS
  • Chromatography
  • TLC
  • Quality Assurance
  • Dissolution
  • XRF
  • Automated Robotic...
  • GMP
  • UV/Vis
  • Analytical Chemistry

Education

North East Surrey College of Technology

HNC Applied Biology(Biochemistry), Biochemistry, Physiology& Pharmacology

Elmwood High School

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